[HTML][HTML] Remdesivir and its antiviral activity against COVID-19: A systematic review

A Frediansyah, F Nainu, K Dhama, M Mudatsir… - … epidemiology and global …, 2021 - Elsevier
Background To summarize the antiviral activities of remdesivir against SARS-CoV-2, the
causative agent of COVID-19. Methods Available publications were systematically explored
on some databases and gray literature was examined. Publications were discussed
narratively. Results Remdesivir inhibits SARS-CoV-2 replication, reduces viral load, and
exerts protective effects in SARS-CoV-2 infected animals. Remdesivir also reduces the
pathological process, alleviates mild symptoms, and improves pulmonary lesions in SARS …