Effect of high-dose vitamin D3 on hospital length of stay in critically ill patients with vitamin D deficiency: the VITdAL-ICU randomized clinical trial
K Amrein, C Schnedl, A Holl, R Riedl, KB Christopher… - Jama, 2014 - jamanetwork.com
Importance Low vitamin D status is linked to increased mortality and morbidity in patients
who are critically ill. It is unknown if this association is causal. Objective To investigate
whether a vitamin D 3 treatment regimen intended to restore and maintain normal vitamin D
status over 6 months is of health benefit for patients in ICUs. Design, Setting, and
Participants A randomized double-blind, placebo-controlled, single-center trial, conducted
from May 2010 through September 2012 at 5 ICUs that included a medical and surgical …
who are critically ill. It is unknown if this association is causal. Objective To investigate
whether a vitamin D 3 treatment regimen intended to restore and maintain normal vitamin D
status over 6 months is of health benefit for patients in ICUs. Design, Setting, and
Participants A randomized double-blind, placebo-controlled, single-center trial, conducted
from May 2010 through September 2012 at 5 ICUs that included a medical and surgical …
