FAs are mobilized from triglyceride (TG) stores during exercise to supply the working muscle
with energy. Mice deficient for adipose triglyceride lipase (ATGL-ko) exhibit defective
lipolysis and accumulate TG in adipose tissue and muscle, suggesting that ATGL deficiency
affects energy availability and substrate utilization in working muscle. In this study, we
investigated the effect of moderate treadmill exercise on blood energy metabolites and liver
glycogen stores in mice lacking ATGL. Because ATGL-ko mice exhibit massive …