Interleukin-1β, interleukin-1 receptor antagonist, interleukin-6, interleukin-10, and tumor necrosis factor-α levels in CSF and serum in relation to the clinical diversity of …
MN Karpenko, AA Vasilishina, EA Gromova… - Cellular …, 2018 - Elsevier
Several parameters representing the clinical diversity of Parkinson's disease (PD), including
severity, phenotypes, cognitive decline, anxiety and depression were analyzed to examine
the link with interleukin-1β (IL-1β), the interleukin-1 receptor antagonist (IL-1RA), IL-6, IL-10,
and tumor necrosis factor-α (TNFα) and also to determine the relationship between levels of
these factors in serum and cerebrospinal fluid (CSF). Significantly elevated serum IL-1β and
IL-6 and reduced IL-1RA levels were found in the PD group. In CSF and serum …
severity, phenotypes, cognitive decline, anxiety and depression were analyzed to examine
the link with interleukin-1β (IL-1β), the interleukin-1 receptor antagonist (IL-1RA), IL-6, IL-10,
and tumor necrosis factor-α (TNFα) and also to determine the relationship between levels of
these factors in serum and cerebrospinal fluid (CSF). Significantly elevated serum IL-1β and
IL-6 and reduced IL-1RA levels were found in the PD group. In CSF and serum …
