Background & Aims Hepatic fibrosis, featured by the accumulation of excessive extracellular
matrix in liver tissue, is associated with metabolic disease and cancer. Inhalation exposure
to airborne particulate matter in fine ranges (PM 2.5) correlates with pulmonary dysfunction,
cardiovascular disease, and metabolic syndrome. In this study, we investigated the effect
and mechanism of PM 2.5 exposure on hepatic fibrogenesis. Methods Both inhalation
exposure of mice and in vitro exposure of specialized cells to PM 2.5 were performed to …