Gender and sex differences in adipose tissue
Current diabetes reports, 2018•Springer
Abstract Purpose of Review As the ongoing epidemic of adult and childhood obesity grows,
it puts a greater burden on individuals and the healthcare system due to increased
prevalence of obesity-associated diseases. An important area that has gained much
attention recently is the sex and gender difference related to obesity and associated
complications. Basic science and clinical studies have now improved our understanding of
obesity and have discovered adipose tissue biology to be key in metabolism. Recent …
it puts a greater burden on individuals and the healthcare system due to increased
prevalence of obesity-associated diseases. An important area that has gained much
attention recently is the sex and gender difference related to obesity and associated
complications. Basic science and clinical studies have now improved our understanding of
obesity and have discovered adipose tissue biology to be key in metabolism. Recent …
Purpose of Review
As the ongoing epidemic of adult and childhood obesity grows, it puts a greater burden on individuals and the healthcare system due to increased prevalence of obesity-associated diseases. An important area that has gained much attention recently is the sex and gender difference related to obesity and associated complications. Basic science and clinical studies have now improved our understanding of obesity and have discovered adipose tissue biology to be key in metabolism.
Recent Findings
There is evidence related to the sex dichotomy in obesity in a variety of areas including adipocyte function, sex hormone effects, genetics, and metabolic inflammation leading to critical differences in adipose tissue biology.
Summary
The sex and gender difference in adipose tissue is a factor that should be considered when studying an individuals’ risk for obesity and metabolic dysfunction. This understanding is important for strategizing treatment and prevention measures.
Springer
